Monday, October 10, 2011

Neurotic Stupidity

I know someone who locks her keys in the car whenever she is in a hurry to get somewhere. Plane leaves in an hour? Her keys are in the car – potentially it’s running and her cell phone mocks her from its perch in the passenger seat. Important meeting? You guessed it…keys safely locked inside the car.

The stress of making a flight or arriving on-time for a meeting is the straw that breaks the proverbial camel’s back. My friend suffers from neurotic stupidity.

Of course, locking her keys in her car is just one symptom. She’s also been known to confuse her children’s names, her phone number and forget to pick up the aforementioned children from soccer practice.

What can she do about neurotic stupidity?

Stress and tension are the roots of the problem. Learning to manage them will help her think more clearly and concentrate more easily.

Easy things she can do include:

Regular aerobic exercise – even if it’s just a brisk thirty-minute walk

If she learns to manage her stress and tension, she just might remember when her daughter’s next soccer game is.

Moira

Tuesday, October 4, 2011

Stress and Cancer

What does stress have to do with cancer?

Cancer is a problem of uncontrolled growth – the cells grow out of control and faster than they should. Cancer is an activation of growth genes – called oncogenes.

Most studies relating stress to cancer have been done in the laboratory with animals. In those studies, findings suggest that stress may bring on cancer and accelerate the progression of cancer.

The problem with the studies is that they inject the animals with cancer cells prior to or after they subject them to stressors. Do you see the problem? We aren’t injected with cancer cells, so we really can’t say that these lab animal studies are pertinent to human cancer.

In human studies, proving stress as a cause of cancer relationship is difficult. Most human studies are retrospective – taking place after someone has been diagnosed with cancer.

Prospective studies are more meaningful. These are the studies that follow people from a younger age into old age and look at different variables, including rates of disease. Here, the cancer/stress relationship falls apart.

What about the stress/relapse relationship? Not much evidence here either – the evidence is minimal.

And finally, what about the rate of progression and stress? Recent research suggests there may be a relationship between progression and stress.

John Cacioppo, PhD, from the University of Chicago and Steve Cole, PhD, from the University of California, Los Angeles are studying the way genes and environment interact to influence behavior and health – called social genomics, a division of molecular biology.

Here is what they are finding:

  • Loneliness and social adversity (including stress) influence health by priming the immune system to use its inflammatory response more often, which increases risk for disease. They are able to peer into cells and see what’s going on at a molecular level in a way that has never been done before.
  • Loneliness and adversity reprogram the immune system to be ready for trouble. This is also true for early life adversity, regardless of current conditions – these situations cause the immune system to be vigilant for stress and tone deaf to cortisol (hormone that controls inflammation), so the pro-inflammatory response proceeds unrestrained creating an increased risk for cardiovascular disease and some cancers.

Susan Lutgendorf, PhD, from the University of Iowa and Steve Cole, PhD, from UCLA found that social circumstances influence gene expression in cancer cells. More than 220 genes were turned on in the cancer cells of women with low levels of social support and high levels of depression. These same genes were not active in women who did not have social stress. Some of those genes are associated with higher rates of cancer metastases.

  • Genes and environment are not separate things.
  • The environment controls what your genome becomes.
  • Social support and stress management help people live better with and possibly control their disease.
  • It is imperative that people living with cancer and heart disease (and most likely other serious illness) have strong support systems and skills to manage stress.

Overall, the science isn’t there to suggest that stress directly effects whether or not we get cancer. Our bodies are much too elegant and complicated to make such a simple statement. However, once someone has cancer, it is in their best interest to do as much as they can to help support their emotional and physical health in order to live as well as they can for as long as they can.

Moira

Tuesday, September 27, 2011

What we can learn from Osmosis Jones

Did you ever see the movie Osmosis Jones? It was on television a few nights ago and I watched it.

Osmosis Jones (voiced by Chris Rock) is a cell that lives in Frank (played by Bill Murray). Frank doesn’t take particularly good care of himself and Osmosis and his fellow ‘cops’ have a tough time keeping Frank healthy. It is their job to identify pathogens and either attack them or create antibodies to neutralize them. Besides being an animated cop, Osmosis is an immune cell.

Osmosis taking out a pathogen.


There are two categories of immune cells, also called lymphocytes – T Cells, which originate in the thalamus, and B Cells, which originate and mature in the bone marrow.

Bill Murray’s character, Frank, has practically no stress in his life. His biggest concern seems to be getting to the Buffalo Wing Festival.

For those of us with more on our minds than wings and dipping sauces, stress is a concern. When you activate your immune system over and over again with short term stressors, you increase the likelihood of the immune system overreacting and wreaking havoc with your health – which can trigger autoimmune diseases or make any condition you already have worse.

Learning how to effectively manage stress is essential to long-term health.

Meditation, relaxation and regular aerobic exercise can all help you stay healthy.

At the end of the movie, Osmosis Jones saves the day (or Frank) and Frank decides to make healthier choices – including exercise and a more balance diet (think vegetables instead of chicken wings).

Like Frank, we can make a conscious decision to lead healthier life-styles. Even small changes can yield big results.

Moira

Thursday, September 22, 2011

Brain Food

‘Oxide’ is a chemical term. It refers to a compound in which oxygen is bonded to one or more electropositive atoms. It makes me think about the rust on a bicycle fender, a cut apple that turns brown or a green penny. Oxidation is NOT something I want happening in my brain.

The brain consumes a large quantity of oxygen, making it susceptible to oxidative stress.

What to do?

Try introducing naturally occurring antioxidants into your diet. Antioxidants  convert free radicals to harmless waste products that are eliminated from the body before any damage is done.

Think of antioxidants act as scavengers that help prevent cell and tissue damage.

Knowing which foods have the most antioxidants is important, because your body needs all the help it can get to fight disease-causing free radicals.

The top ten antioxidant rich foods?
 
1) Small red beans (dried)
 
2) Wild blueberries.
 
3) Red Kidney beans.
 
4) Pinto beans.
 
5) Blueberries (cultivated)
 
6) Cranberries.
 
7) Artichokes (cooked)
 
8) Blackberries
 
9) Prunes
 
10) Raspberries
 
Don’t forget spices – especially powerful are cloves, turmeric and cocoa. McCormick has a handy chart.

Finally, you can drink antioxidants. Grape juice, red wine, green tea and pomegranate juice are all excellent choices.

Bon Appetit!

Moira

Tuesday, September 20, 2011

Staying Sharp

In 1950, people could expect to live about eight years after retirement. In 2011, retirees can expect to live for 20 years. The difference is due to increased life expectancy and earlier retirement ages. No matter how old you are, there are things you can do NOW to ensure you enjoy a vibrant, healthy retirement with an active, curious mind.

The factors most closely linked with maintained mental function late in life include:

           Higher Education – This doesn’t mean you have to go back to school. What researchers think is that people who pursue a graduate degree are curious and that school teaches you how to learn.
           Aerobic exercise
           Traveling
           Hobbies – especially complex hobbies like playing bridge or chess
           Learning a new language
           Learning to play a musical instrument

Another tip - watch less TV – your brain goes into neutral and that’s not a good thing.

Also, don’t overlook exercise! Even a brisk daily walk can yield big returns.

 
The brain begins to lose nerve tissue beginning at age 30 (yikes!). Aerobic exercise tends to reinforce neural connections by increasing the number of dendrite connections between neurons, creating a denser network. A dense network is better able to process and store information. Exercise may even aid with the production of new neurons.
 
As if that wasn’t enough, aerobic exercise is strongly protective of brain functions. And, the effect is largest if you start in middle age.

And, it’s not just your brain that will benefit. Regular exercise leads to:

·         Improved cardio health
·         Reduction of depression
·         Better cardiovascular function
·         Better bone health
·         Better body composition

Think of it as saving for the future – your future health!

Moira

Thursday, September 15, 2011

Increasing Willpower

The ability to resist impulses and delay gratification (or willpower) is highly associated with success in life.

What limits willpower? What enhances it? It might be blood sugar, an essential energy source for brain cells. Most cognitive functions aren’t affected by minor blood sugar fluctuations. Planning and self-control are. 

In essence, exerting self-control lowers blood sugar, which reduces the capacity for further self-control. This is how diet might play a role in will-power. Certain foods that help regulate blood sugar, like those containing protein or complex carbohydrates, may enhance willpower for longer periods.

Imagine you have a willpower budget – one that you can spend bypassing temptation or making yourself complete unloved tasks. How you spend your budget is up to you.

The good news? You can increase your budget. Willpower can grow in the long term. Like a muscle, it seems to become stronger with use. The idea of exercising willpower is seen in military boot camp, where recruits are trained to overcome one challenge after another.

Use your non-dominant hand to brush your teeth for two weeks. Believe it or not, this can lead to a measurable increase in your willpower capacity. People who do this can stick with an exercise program or diet longer. It also reduces impulsive spending, smoking, and eating junk food.

Also, people who stick to an exercise program for two months report reducing their impulsive spending, junk food intake, alcohol use and smoking. They also study more, watch less television and do more housework.

The growth of willpower reflects a biological change in the brain. It could be that the neurons in the frontal cortex (responsible for planning behavior) or in the anterior cingulate cortex (associated with cognitive control) use blood sugar more efficiently after repeated challenges. Perhaps the chemical messengers that neurons use to communicate with one another are produced in larger quantities after they have been used up repeatedly.

Whatever the explanation, consistently doing any activity that requires self-control seems to increase willpower.

May the force be with you.

Moira

Tuesday, September 13, 2011

While Your Were Sleeping

What happens while you sleep?

The first stage of sleep is slow-wave sleep where most of your brain is inactive which allows for restoration of energy in your nervous system.

The second stage of sleep is REM sleep (rapid eye movement) where some parts of your brain are silent while other parts are very active. During REM sleep the secondary sensory cortex is more active.

When you are awake and see something, the stimuli comes in through your retina, through your primary visual cortex, then over to your secondary and tertiary visual cortices, etc. But during REM sleep, the activity starts in the secondary and tertiary cortices rather than the primary visual cortex. In other words, those parts of your brain are processing things even though you aren’t actually seeing anything – you are dreaming.

Why do you need sleep?

First off, to restore energy to your brain. While the brain account for only 3% of your body weight, it uses 20-25% of your energy. Unfortunately, your brains cells cannot store energy. You need to replenish your reserves with sleep.

Another very important function of sleep is the consolidation of memories (particularly during REM). If your REM sleep is disrupted, it interferes with your cognition – you won’t remember or learn things as well.

Dreaming is an important activity during sleep. The subcortical/subconscious communicates in the form of images – dream images. Dreaming is also a chance to use circuits in your brain that you may have underused during the day.

Lack of sleep or sleep deprivation is a stressor.  Levels of glucocorticoids rise when you are sleep deprived. This can affect your bodies ability to form long-term memory, your metabolism and your immune systems – and not in a good way.

One way to improve the quality and length of sleep is by practicing a meditation/relaxation exercise right before you go to bed. It will help you sleep more soundly and keep you from waking up as often.

Moira